Neuroscience Terms For Education

Neuroscience Terms For Educators

contributed by Judy Willis M.D., M.Ed., radteach.com and Rae Nishi, PhD

Affective Filter

Definition: The affective filter is an emotional state of stress in children during which they are not responsive to processing, learning, and storing new information. This affective (emotional) filter is in the amygdala, which becomes hyperactive during periods of high stress. In this hyperstimulated state, new information does not pass through the amygdala to reach the higher thinking centers of the brain.

Classroom Example: A student experiencing test anxiety may find it difficult to focus or retain information during a review session, as the affective filter prevents learning from taking place.

Citation: Krashen, S. D. (1982). Principles and Practice in Second Language Acquisition. Pergamon Press.

Amygdala

Definition: Part of the limbic system in the temporal lobe. The amygdala was first believed to function as a brain center for responding only to anxiety and fear. When the amygdala senses a threat, it becomes activated (high metabolic activity as seen by greatly increased radioactive glucose on positron emission tracing (PET) and oxygen use in functional magnetic resonance imaging (fMRI). These neuroimaging findings show that when children feel helpless and anxious, the amygdala is activated; thus, new information coming through the sensory intake areas of the brain cannot pass through the amygdala’s affective filter to gain access to memory circuits.

Classroom Example: When a teacher creates a safe and welcoming environment, students are less likely to feel threatened, keeping the amygdala calm and more open to learning experiences.

Citation: LeDoux, J. E. (1996). The Emotional Brain: The Mysterious Underpinnings of Emotional Life. Simon & Schuster.

Attention

Definition: The selective focus on certain stimuli while ignoring others; a prerequisite for encoding information into memory.

Classroom Example: A teacher dims the lights and reduces distractions during a lesson on poetry to help students concentrate on the spoken words and rhythm.

Citation: Posner, M. I., & Rothbart, M. K. (2007). Research on attention networks as a model for the integration of psychological science. Annual Review of Psychology, 58, 1–23.

Axon

Definition: This is the fiber-like extension of the neuron that connects the cell body to other target cells (neurons, muscles, glands).

Classroom Example: When explaining how the brain sends messages, a teacher uses a diagram showing axons connecting to other neurons and simulates the “message pathway” using string and paper notes.

Brain Imaging (Neuroimaging)

Definition: Non-invasive imaging techniques have contributed to our knowledge of the structure, function, or biochemical status of the brain. Structural imaging such as magnetic resonance imaging (MRI) and computed tomography (CT) scans reveal the overall structure of the brain. Functional magnetic resonance imaging (fMRI) provides visualization of the processing of neural activity in the brain while a subject is conscious and performing tasks. This processing is visualized directly as areas of the brain that are “lit up” by increased blood flow and oxygenation. Positron-emission tomography (PET) provides information about the quantity of important chemicals in the brain such as neurotransmitters, which are substances used by neurons to communicate with other neurons and end organs.

Classroom Example: During a brain science unit, students explore images from fMRI scans and compare how different parts of the brain activate when performing tasks like speaking or solving puzzles.

Brain Mapping

Definition: Using electroencephalography (EEG) or functional MRI over time, brain mapping measures electrical activity representing brain activation along neural pathways. These techniques allow scientists to track which parts of the brain are active when a person is processing information at various stages of information intake, patterning, storing, and retrieval. The levels of activation in particular brain regions are associated with the intensity of information processing.

Classroom Example: A high school biology teacher introduces students to EEGs by showing how different mental tasks activate different brain regions, using visual examples from real studies.

Cerebellum

Definition: This is a large cauliflower-looking structure on the back of the brainstem under the cerebral cortex. This structure is very important in motor movement and motor-vestibular memory and learning.

Classroom Example: When students learn to ride bikes or perform choreography in physical education, their cerebellum helps encode and refine those motor skills through practice.

Citation: Manto, M., & Jissendi, P. (2012). Cerebellum: Links between development, developmental disorders and motor learning. Frontiers in Neuroanatomy, 6, 1.

Cerebral Cortex

Definition: This is the outermost layer of the cerebral hemispheres of the brain. The cortex mediates all conscious activity, including planning, problem-solving, language, and speech. It is also involved in perception, image processing, and voluntary motor activity.

Classroom Example: During project-based learning, students activate their cerebral cortex as they plan, collaborate, and use language to express ideas and solve complex problems.

Citation: Kolb, B., & Whishaw, I. Q. (2015). Fundamentals of Human Neuropsychology (7th ed.). Worth Publishers.

Central Nervous System

Definition: This is the portion of the nervous system composed of the spinal cord and brain.

Classroom Example: In a science class, students build models of the brain and spinal cord to better understand how messages are transmitted through the central nervous system.

Cognition

Definition: This refers to the mental process by which we become aware of the world and use that information to problem solve and make sense out of the world. It is somewhat oversimplified but cognition refers to thinking and all of the mental processes related to thinking.

Classroom Example: When students analyze a character’s motivations in literature or develop hypotheses in science, they are engaging in cognitive processes.

Citation: Anderson, J. R. (2010). Cognitive Psychology and Its Implications (7th ed.). Worth Publishers.

Dendrites

Definition: Branched protoplasmic extensions that sprout from the cell bodies of neurons. Dendrites receive connections from other neurons and coordinate electrical activity that passes down axons. A single neuron may possess many dendrites. Dendrites in cortical neurons increase in size and number in response to learned skills, experience, and information storage. New dendrites grow as branches from frequently activated neurons. Proteins called growth factors stimulate this dendritic growth.

Classroom Example: As students repeatedly practice a musical scale or math skill, their dendrites grow to strengthen those neural pathways, improving long-term retention.

Dopamine

Definition: A neurotransmitter most associated with attention, decision making, executive function, and reward-stimulated learning. Dopamine release from the midbrain has been found to increase in response to rewards and positive experiences. Scans reveal greater activation of dopaminergic areas while subjects are playing, laughing, exercising, and receiving acknowledgment (e.g., praise) for achievement.

Classroom Example: A teacher uses positive feedback and recognition strategies to trigger dopamine release and improve students’ focus and motivation during lessons.

Citation: Schultz, W. (2002). Getting formal with dopamine and reward. Neuron, 36(2), 241–263.

Executive Functions

Definition: Cognitive processing of information that takes place in the prefrontal cortex that exercise conscious control over one’s emotions and thoughts. This control allows for patterned information to be used for organizing, analyzing, sorting, connecting, planning, prioritizing, sequencing, self-monitoring, self-correcting, assessment, abstractions, problem solving, attention focusing, and linking information to appropriate actions.

Classroom Example: A teacher scaffolds a multi-step research project by modeling time management, sequencing tasks, and using checklists to support students’ executive function skills.

Citation: Diamond, A. (2013). Executive functions. Annual Review of Psychology, 64, 135–168.

Glia

Definition: These are specialized cells that nourish, support, and complement the activity of neurons in the brain. Astrocytes are the most common and play important roles in regulating blood flow to activated areas of the brain, regulating the amount of neurotransmitter in the synapse by taking up excess neurotransmitter, and providing important growth factors for modulating neuronal function. Oligodendrocytes wrap axons in myelin, which acts as an insulator so that nerve activity can be rapidly transmitted from area to area of the brain. Microglia are the “macrophages” of the brain and regulate inflammation in the brain.

Classroom Example: While not a topic typically covered directly in K–12 settings, teachers can enhance neuroscience units by showing how glial cells support neural function during tasks like learning new vocabulary or solving puzzles.

Graphic Organizers

Definition: Diagrams that are designed to coincide with the brain’s style of patterning. In order for sensory information to be encoded (the initial processing of the information entering from the senses), consolidated, and stored, the information must be patterned into a brain-compatible form. Graphic organizers can promote this patterning in the brain when children participate in creating relevant connections to their existing memory circuitry.

Classroom Example: During a nonfiction reading lesson, students use a cause-effect chart to organize historical events and connect them to prior knowledge.

Gray Matter

Definition: The gray refers to the darker color of the cerebral cortex and subcortical structures relative to the white matter of axon tracts. The axon tracts appear intensely white because of the myelin surrounding the axons. The myelin contains a very high concentration of lipids and cholesterol, causing a “white” greasy appearance. In contrast to white matter, gray matter contains neurons, dendrites, synapses, and many astrocytes. It is in the gray matter where neural signals are integrated and analyzed.

Classroom Example: A high school anatomy class labels brain models to differentiate between white and gray matter and discuss how each contributes to learning and memory.

Citation: Giedd, J. N., & Rapoport, J. L. (2010). Structural MRI of pediatric brain development: What have we learned and where are we going? Neuron, 67(5), 728–734.

Hippocampus

Definition: The hippocampus is a folded structure in the floor of the ventral horn of each lateral ventricle of the brain that consists mainly of gray matter that has a major role in memory processes. The hippocampus takes sensory inputs and integrates them with relational or associational patterns from preexisting memories, thereby binding the information from the new sensory input into storable patterns of relational memories. This is called memory consolidation. The hippocampus also plays an important role in spatial recognition.

Classroom Example: During a field trip, students remember new content better when the teacher connects it to a previous lesson, activating the hippocampus’s role in memory consolidation.

Citation: Squire, L. R., & Zola-Morgan, S. (1991). The medial temporal lobe memory system. Science, 253(5026), 1380–1386.

Limbic System

Definition: This is a group of functionally linked structures in the brain (hippocampal formation, amygdala, septal nuclei, cingulate cortex, entorhinal cortex, perirhinal cortex, and parahippocampal cortex). The limbic system is involved in regulation of emotion, memory, and processing complex socio-emotional communication.

Classroom Example: A classroom that supports emotional safety and collaborative discussion can engage the limbic system in ways that improve both memory and motivation.

Citation: Rolls, E. T. (2015). Limbic systems for emotion and for memory, but no single limbic system. Cortex, 62, 119–157.

Long-Term Memory

Definition: Long-term memory is created when short-term memory is strengthened through review and meaningful association with existing patterns and prior knowledge. This strengthening results in a physical change in the structure of neuronal circuits.

Classroom Example: A teacher helps students retain science vocabulary by repeatedly connecting terms to diagrams, stories, and real-life examples over time.

Long-Term Memory

Definition: Long-term memory is created when short-term memory is strengthened through review and meaningful association with existing patterns and prior knowledge. This strengthening results in a physical change in the structure of neuronal circuits.

Classroom Example: A teacher helps students retain science vocabulary by repeatedly connecting terms to diagrams, stories, and real-life examples over time.

zed.

Classroom Example: A high school anatomy class labels brain models to differentiate between white and gray matter and discuss how each contributes to learning and memory.

Citation: Giedd, J. N., & Rapoport, J. L. (2010). Structural MRI of pediatric brain development: What have we learned and where are we going? Neuron, 67(5), 728–734.

Metacognition

Definition: Knowledge about one’s own information processing and strategies that influence one’s learning that can optimize future learning. After a lesson or assessment, when children are prompted to recognize the successful learning strategies they used, that reflection can reinforce the effective strategies.

Classroom Example: After completing a challenging writing assignment, students discuss which strategies helped them stay organized and how they could improve next time.

Citation: Flavell, J. H. (1979). Metacognition and cognitive monitoring: A new area of cognitive–developmental inquiry. American Psychologist, 34(10), 906–911.

Myelin

Definition: The fatty substance that covers and protects nerves. Myelin is a layered tissue that sheathes the axons (nerve fibers). This sheath around the axon acts like an insulator in an electrical system, ensuring that messages sent by axons are not lost as they travel to the next neuron. Thus, myelin increases the speed of nerve impulses.

Classroom Example: A teacher explains that repeated practice of multiplication facts strengthens brain pathways and improves fluency as myelin wraps more securely around frequently used axons.

Myelination

Definition: The formation of the myelin sheath around a nerve fiber.

Classroom Example: Students who practice the same reading strategy regularly develop more efficient pathways in the brain as myelination improves processing speed.

Citation: Fields, R. D. (2008). White matter in learning, cognition and psychiatric disorders. Trends in Neurosciences, 31(7), 361–370.

Neuronal Circuits

Definition: Neurons communicate with each other by sending coded messages along electrochemical connections called synapses. When there is repeated stimulation of specific patterns of activity between the same groups of neurons, their synapses change, and the efficiency of communication becomes stronger. This is where practice (repeated stimulation of grouped neuronal connections in neuronal circuits) results in more successful recall.

Classroom Example: A student who repeatedly practices spelling a word strengthens the neuronal circuit associated with that word, improving recall over time.

Neurons

Definition: Specialized cells in the brain and throughout the nervous system that control storage and processing of information to, from, and within the brain, spinal cord, and nerves. Neurons are composed of a cell body that houses the nucleus, a single major axon for outgoing electrical signals, and a varying number of dendrites that receive synapses from other neurons.

Classroom Example: In a neuroscience unit, a teacher uses pipe cleaners and beads to help students build neuron models and identify dendrites, axons, and synapses.

Citation: Purves, D. et al. (2012). Neuroscience (5th ed.). Sinauer Associates.

Neuroplasticity

Definition: This refers to the remarkable capacity of the brain to change its molecular, microarchitectural, and functional organization in response to injury or experience. Dendrite formation and destruction (pruning) alters the number of synapses on neurons and allows the brain to reshape and reorganize the networks of connections in response to increased or decreased use of these pathways.

Classroom Example: A student who struggles with reading can strengthen reading circuits through consistent, targeted practice thanks to the brain’s plasticity.

Neurotransmitters

Definition: Molecules that are released by the electrical impulses on one side of the synapse (axonal terminal) and then float across the synaptic gap carrying the information with them to stimulate the nerve ending (dendrite) of the next cell in the pathway. Once the neurotransmitter binds to protein receptors on the dendrite, an electric impulse is generated.

Neurotransmitters in the brain include glutamate, gamma-amino butyric acid (GABA), serotonin, acetylcholine, dopamine, norepinephrine and many others.

Classroom Example: A teacher uses color-coded visuals to help students differentiate major neurotransmitters and their roles during a psychology unit.

Numeracy

Definition: The ability to reason with numbers and other mathematical concepts. Children’s concepts of number and quantity develop with brain maturation and experience.

Classroom Example: A kindergarten teacher uses hands-on manipulatives and number games to develop early numeracy by connecting quantities to symbols and vocabulary.

Occipital Lobes (Visual Processing Areas)

Definition: These posterior lobes of the brain process information from the eyes so we recognize objects we see and connect these objects to words, meaning, and action.

Classroom Example: When students examine visual diagrams in a biology textbook, their occipital lobes are activated to help them identify and label the parts of a cell.

Citation: Grill-Spector, K., & Malach, R. (2004). The human visual cortex. Annual Review of Neuroscience, 27, 649–677.

Oligodendrocytes

Definition: Oligodendrocytes are the glia in the brain and spinal cord that specialize to form the myelin sheath around many axons.

Classroom Example: A high school neuroscience class might explore how oligodendrocytes support fast thinking and movement by discussing demyelinating disorders like multiple sclerosis.

Parietal Lobes

Definition: Parietal lobes on each side of the brain process somatosensory information (sensations of touch, pain, limb movement, and knowledge of where body parts are in space) and integrate it with memory and other functions.

Classroom Example: Students learning to play an instrument or type on a keyboard rely heavily on their parietal lobes to coordinate sensory input with fine motor memory.

Citation: Andersen, R. A. (1997). Multimodal integration for the representation of space in the posterior parietal cortex. Philosophical Transactions of the Royal Society B, 352(1360), 1421–1428.

Patterning

Definition: Patterning is the process whereby the brain perceives sensory data and generates patterns by relating new information with previously learned material or chunking material into pattern systems it has used before. Education is about increasing the patterns children can use, recognize, and communicate. As the ability to see and work with patterns expands, the executive functions are enhanced. Whenever new material is presented in such a way that children see relationships, they can generate greater brain cell activity (formation of new neural connections) and achieve more successful patterns for long-term memory storage and retrieval.

Classroom Example: In a math lesson on multiplication, students use pattern blocks to discover multiples and develop rules based on observed visual patterns.

Prediction

Definition: Prediction is what the brain does with the information it patterns. Prediction occurs when the brain has enough information in a patterned memory category that it can find similar patterns in new information and predict what the patterns mean. For example, if you see the number sequence 3,6,9,12… you predict the next number will be 15 because you recognize the pattern of counting by threes.

Through careful observation, the brain learns more and more about our world and is able to make more and more accurate predictions about what will come next. Prediction is often what is measured in intelligence tests. This predicting ability is the basis for successful reading, calculating, test taking, goal-setting, and appropriate social interactions behavior. Successful prediction is one of the best problem-solving strategies the brain has.

Classroom Example: A teacher pauses during a read-aloud and asks students to predict what will happen next, encouraging them to use prior knowledge and text clues.

Prefrontal Cortex

Definition: The prefrontal cortex (PFC) is a hub of neural networks with intake and output to almost all other regions of the brain. In the PFC relational, working-memories can be mentally manipulated to become long-term memory and emotions can be consciously evaluated.

Executive functions directed by PFC networks respond to input through the highest levels of cognition. These functions include information evaluation, prediction, conscious decision making, emotional awareness and response, organizing, analyzing, sorting, connecting, planning, prioritizing, sequencing, self-monitoring, self-correcting, assessment, abstraction, deduction, induction, problem solving, attention focusing, and linking information to planning and directing actions.

Classroom Example: A teacher asks students to evaluate different sources when conducting a research project, activating PFC networks for critical thinking and judgment.

Citation: Miller, E. K., & Cohen, J. D. (2001). An integrative theory of prefrontal cortex function. Annual Review of Neuroscience, 24, 167–202.

Pruning

Definition: Neural connections are pruned (destroyed) when they are not used. In a baby, the brain overproduces brain cells (neurons), which are eliminated in the fetus. The remaining neurons make a large number of connections between brain cells (synapses), which are then pruned around the age of three. The second wave of synapse formation occurs just before puberty and is followed by another phase of pruning. Pruning allows the brain to consolidate learning by removing inefficient or little-used synapses, while strengthening remaining synapses. In parallel, myelination speeds neural processing by wrapping more white matter (myelin) around axons that are frequently used.

Classroom Example: Educators can support pruning by giving students time to practice and apply skills, ensuring that commonly used pathways are reinforced while less relevant ones are naturally eliminated.

RAD Learning

Definition: There are three main brain systems (reticular activating system, amygdala, dopamine (RAD)) that are keys to building better brains. These three systems can also be referred to as Reach and Discover.

Classroom Example: A teacher designs engaging, emotionally relevant learning tasks that activate the RAD system—like student choice, novelty, movement, and opportunities for positive feedback.

Citation: Willis, J. (2007). Research-Based Strategies to Ignite Student Learning. ASCD.

Reticular Activating System (RAS)

Definition: This lower part of the posterior brain filters all incoming stimuli and makes the ‘decision’ as to what sensory input is attended to or ignored. The main categories that focus the attention of the RAS include novelty (changes in the environment), surprise, danger, and movement.

Classroom Example: A teacher begins class with a surprising fact or question to immediately engage the RAS and direct student attention toward the topic at hand.

Serotonin

Definition: A neurotransmitter used to carry messages between neurons. Too little serotonin may be a cause of depression and inattention. Dendritic branching is enhanced by the serotonin secreted by the brain predominantly between the sixth and eighth hour of sleep (non-REM).

Classroom Example: Teachers who encourage healthy sleep habits in young learners support serotonin regulation, which can enhance attention and emotional balance in class.

Citation: Jacobs, B. L., & Azmitia, E. C. (1992). Structure and function of the brain serotonin system. Physiological Reviews, 72(1), 165–229.

Short-Term Memory (Working Memory)

Definition: This memory can hold and manipulate information for use in the immediate future. Information is only held in working memory for about a minute. The working memory span of the mature brain (less in children) is approximately 7-9 chunks of data. You can read more about teaching around the way short and long-term memory work here via the Cognitive Load Theory.

Classroom Example: When solving a multi-step math problem, students hold interim calculations in working memory while completing the full equation.

Citation: Baddeley, A. (1992). Working memory. Science, 255(5044), 556–559.

Synapse

Definition: Synapses are functional connections between neurons, typically an axon terminal from one neuron (the presynaptic cell) touching a dendrite of another (the postsynaptic cell). Neurotransmitters in the axon terminal are released by nerve activation of the presynaptic cell and travel across the synapse to bind to receptors on the dendrite of the postsynaptic cell. Once the neurotransmitter is bound to its receptors, it triggers a change in membrane potential that affects the activity of the postsynaptic neuron.

Classroom Example: To explain how messages move through the brain, a teacher simulates a synapse using students passing a ball (representing a neurotransmitter) between two desks labeled “axon terminal” and “dendrite.”

Citation: Kandel, E. R., Schwartz, J. H., & Jessell, T. M. (2000). Principles of Neural Science (4th ed.). McGraw-Hill.